INST Faculty Directory
Dr. Deepa Ghosh
Professor (Scientist-F )
Educational Qualification:
  • PhD: Birla Institute of Technology and Science (BITS), Pilani, India; Uniformed Services University of the Health Sciences Bethesda, MD. USA, (Off site)
  • M. Pharm: Birla Institute of Technology and Science (BITS), Pilani, India
  • B.Pharm: Madras University  

  • Awards
    • Recipient of the NASI-Reliance Innovation award (2012)

    • Best research award from Henry M. Jackson Foundation for the Advancement of Military Medicine (1994) 

    Positions Held ::
  • Professor (Scientist-F), Institute of Nano Science and Technology,  Mohali, India. (Sep 2016 onwards)
  • Freelance Consultant (2014-2016)
  • Associate Research Director, Reliance Life Sciences, Navi- Mumbai, Maharashtra, India  (2009-2014)
  • Assistant Research Director, Tissue Engineering and Wound Management, Reliance Life Sciences, Navi- Mumbai, Maharashtra, India (2005-2009)
  • Senior Research Scientist, Tissue Engineering, Reliance Life Sciences, Mumbai, India (2001-2004)
  • Research Scientist I, Pharmacology Department, Glenmark Pharma, Mumbai, India (2000-2001)
  • Research Leader, Natural products, Quest Institute, Nicholas Piramal, Mumbai, India (1999-2000)
  • Postdoctoral research fellow, Emory University, Atlanta, GA, USA (1996-1999)
  • Research Fellow, Henry M. Jackson Foundation, USUHS, MD, USA  (1992-1996) 
  • Lecturer, Department of Pharmacy, Birla Institute of Technology and Sciences, Pilani, India (1991-1992) 

  • Research interests :
  • Tissue engineering using nanostructured scaffolds. Cell delivery using nanocomposites. Addressing wound management with low cost devices. 


  • Selected Publications
    1. P. Kuchroo, V. Dave, A. Kumar, C. Viswanathan and D. Ghosh* (2015) Paracrine factors secreted by umbilical cord-derived MSCs induce angiogenesis in vitro by a VEGF-independent pathway. Stem Cells and Development 24(4): 437-450. (Cited 12) IF 4.2
    2. A. Das, A.Kumar, N.Patil, C. Viswanathan and D. Ghosh* (2015) Preparation and characterization of silver nanoparticle loaded amorphous hydrogel of carboxymethylcellulose for infected wounds. Carbohydrate Polymers 130, 254–261 (Cited 6) IF 4.07
    3. B. Bandyopadhyay, A. Thakur, V. Dave, C.Viswanathan and D. Ghosh* (2014) A Non-invasive Method to Evaluate the Efficacy of Human Myoblast in Botulinum-A Toxin Induced Stress Urinary Incontinence Model in Rats. Urology Journal 10, no. 4: 1126-1134. (Cited 1) IF 2.27
    4. C. Viswanathan, P. Shetty, S. Sarang, K .Cooper, D. Ghosh and A. Bal (2013) Role of cell therapy in non-healing diabetic ulcers in patients with severe peripheral arterial disease – a preliminary report on five cases. The Journal of Diabetic Foot Complications, 2013; Volume 5, Issue 1, 1: 1-14
    5. B. Bandyopadhyay, V. Shah, M. Soram, C. Viswanathan and D. Ghosh* (2013). In Vitro and In Vivo Evaluation of L-lactide/ε-caprolactone copolymer Scaffold to support Myoblast Growth and Differentiation. Biotechnology Progress 29:197-205 (Cited 7) IF 2.1.
    6. D. Ghosh*, P.Kuchroo, C.Viswanathan, S.Sachan, B.Shah, D.Bhatt, S.G.Parasramani and S.Savant (2012). Efficacy and safety of Autologous Cultured Melanocytes delivered on Poly(DL-lactic acid) film (ReliDerm®M) in the treatment of Stable Vitiligo: Results of a prospective open labeled, randomized, multicentre study. Dermatol Surg 10; 1–10 (Cited 4) IF 1.86
    7. M. Deshpande, S. Tipnis, P. Shetty, D. Ghosh and C. Viswanathan, (2010) Immunologic properties of human dermal fibroblasts. Human Immunology vol. 71, 1089-1098 (Cited 7) IF 2.87.
    8. D. Ghosh*, S. Shenoy and P. Kuchroo. (2008) Cultured Melanocytes: From skin biopsy to transplantation. Cell Transplantation, 17(3):351-60 (Cited 9) IF 6.2  
    9. D. Thaloor, J. Gephardt, K. Miller and GK. Pavlath (1999) Systemic administration of the NF-kappa B inhibitor curcumin stimulates muscle regeneration after traumatic injury. Am.J. Physiol. 277(2 Pt 1):C320-C329 (Cited 153) IF 7.65.
    10.  K.Miller, D. Thaloor, S. Matteson and GK. Pavlath. (1999) Hepatocyte Growth Factor induces myoblast proliferation but inhibits its differentiation in vivo. Am J Physiol Cell Physiol. Jan; 278 (1):C174-81 (Cited 201) IF 4.01
    11. D. Thaloor, AK. Singh, GS. Sidhu, PV. Prasad, H.Kleinman and RK. Maheshwari. (1998)   Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by Curcumin. Cell Growth and Differentiation 9(4):305-312 (Cited 200) IF 4.69
    12. GK. Pavlath, D. Thaloor, TA. Rando, M. Cheong, AW. English and B.Zheng. (1998) Heterogeneity among muscle precursor cells in adult skeletal muscles with differing regenerative capacities. Developmental Dynamics 212:495-508 (Cited 116) IF 2.59
    13. KL. Abbott, B. Friday, D. Thaloor, TJ. Murphy and GK. Pavlath. (1998) Activation and Cellular localization of the Cyclosporine A- sensitive transcription factor NF-AT in skeletal muscle cells. Mol. Bio. Cell 9(10) 2905-16 (Cited 220) IF 7.3
    14. GS.  Sidhu, AK. Singh, D. Thaloor, KK. Banaudha, G. Patnaik, RC. Srimal and RK. Maheshwari. (1998) Enhancement of Wound Healing by Curcumin in animals. Wound Repair and Regeneration 6(2) 167-77 (Cited 206) IF 2.757
    15. GS. Sidhu, D. Thaloor, AK. Singh, PN. Raghunath and RK. Maheshwari. (1996) Enhanced biosynthesis of extracellular matrix proteins and TGF-b by Polyinosinic-Polycytidylic acid during cutaneous wound healing in vivo. J. Cell. Physiol. 169(1):108-114 (Cited 10) IF 4.218
    16. AK. Singh, GS. Sidhu, D. Thaloor and RK. Maheshwari. (1996) Curcumin inhibits the proliferation and cell cycle progression of human umbilical vein endothelial cell. Cancer Lett. 107:109-115 (Cited 106 )IF 4.54
    Patents
    1. Device for culturing and transporting cells. Deepa Ghosh and Sudheer Shenoy (US Patent 7,713,734; EP Patent 1,979,465).
    2. Insert Device for culturing cells. Deepa Ghosh and Pushpa Choudhary (US patent 7,588,932; Indian patent 236218)
    3. Cultured Melanocytes on Bioploymer Membranes for Treatment of Hyper and Hypopigmentation Disorders. Deepa Ghosh, Sudheer Shenoy, Pushpa Kuchroo and Viru Shah (Patent: US 20080089870A1, EP2089076; PCT/IN2007/000489)
    4. An interactive wound cover. Deepa Ghosh, Pushpa Kuchroo, Sudheer Shenoy, Vidhya Rangaswamy, Sonti Venkata Rama Krishna (US 20070258958A1; PCT/IN2007/000060)
    5.  Hydrogel composition. Joydeep Dutta, Deepa Ghosh, Anish Sen Majumdar, Garima Dwivedi and Chandra Viswanathan. (Patent: PCT/IN2009/000707, WO2010067378A2)
    6.  A process for preparing keratinocyte composition as a wound cover. Deepa Ghosh, Pushpa Kuchroo, Sudheer Shenoy, Vidhya Rangaswamy, Sonti Venkata Rama Krishna ( Indian patent No: 243296)
    Invited talks in Select International and National Conferences
    • “Regenerative medicine and Tissue Engineering” in the 82nd Annual Session of the National Academy of Sciences, India and National Symposium on “Nano-science & Technology for Mankind” on Nov 29- Dec  01, 2012 at Banaras Hindu University, Varanasi.
    • “Measures to overcome the challenges facing cell delivery in regenerative medicine” in the Stem Cells 2012 conference in Mumbai Oct.10-11, 2012.
    • “Tissue engineering approach to cell delivery” at International Conference on Emerging Cell Therapies, Chicago, USA October 1-3, 2012.
    • “Safety and effi cacy study of autologous cultured melanocytes delivered on Poly (lactic acid) membrane (ReliDerm®M) in thebtreatment of Stable Vitiligo”. International Conference & Exhibition on Clinical Research Dermatology, 5-6 July 2011 San Francisco, USA
    • “Autologous Cultured Melanocytes delivered on Poly (lactic acid) membrane (ReliDerm®M) in the treatment of Stable Vitiligo: Safety and Efficacy study” at Vitilicon 2011 conference, Bangalore. April 22-24, 2011
    • “Challenges in addressing wounds in India”. Wound healing congress, Dallas, Texas, USA. Apr 14-17, 2011 Texas
    • “Stem Cells and Tissue Engineering: From Bench to bedside” at the International conference on Biomaterials, Artificial organs and Tissue Engineering, Cochin, Mar1-3, 2010
    •  “Chitosan: A potential keratinocyte delivery system for wound management” at the Gordon conference, Plymouth, NH, USA July 29-Aug. 3, 2005.
    •  “Systemic administration of Curcumin an NFkB/AP-1 inhibitor enhances muscle regeneration in mice” at the Gordon conference, Tilton, NH, USA, Aug.16-21 1998.
    • “The effect of HGF on regeneration in mice in the Satellite Meeting”, Boston, MA, USA, Aug. 13-15, 1998.
    • “Inhibition of angiogenesis of Human Umbilical Vein endothelial cells by Curcumin” at the American Society of Cell Biology in Washington DC.,USA, Dec. 10-14, 1995.
    • “Anti-proliferative effect of Curcumin” in the American Society of Cell Biology at San Francisco, CA,USA Dec. 10-14, 1994.
    • “Interferon induced block in the transport of VSV-G in TGN in transfected mouse cells” in The American Society of Cell Biology at New Orleans, LO, USA Dec. 10-14, 1993.
    • “Thymosin-b4 enhances angiogenesis in endothelial cell” in the XVI International Cancer Congress, New Delhi, India 1994.
    • “Brefeldin-A inhibits HTLVIII replication in peripheral blood lymphocytes” in the First National Conference on Human Retroviruses and Related Infections, Washington DC. USA. 1993.
    Products Commercialized

    Wound Management products commercialized: 5; Tissue Engineered products that had undergone clinical trials: 4

     

     

    CONTACT INFORMATION :

    Tel: 0172 - 2210075
    Email Id:

    deepa(dot)ghosh(at)inst(dot)ac(dot)in

    Office Address :

    Institute of Nano Science & Technology
    Habitat Centre, Sector - 64, Phase X, Mohali

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