Dr. Sangita Roy
♦ PhD: 2009, Indian Association for the Cultivation of Science, Kolkata, India.
♦ MSc: 2002, Department of Chemistry, University of Calcutta, India.
♦ BSc: 2000, Department of Chemistry, University of Calcutta, India.
♦ Visiting Scientist, Institute of Nano Science and Technology, Mohali, India (July 2013-January 2014).
♦ Post Doctoral Research Fellow, Department of Pure & Applied Chemistry, University of Strathclyde, Glasgow, UK (2009-2013).
♦ Consultant, BioGelx, Glasgow, UK (2013)
♦ PhD Research Fellow, Department of Biological Chemistry, Indian Association for the Cultivation of Science, Kolkata, India (2004-2009).
♦ Project Associate, ChemBiotek Research International Pvt. Ltd., Kolkata, India (2002-2003).
♦ Our research focuses on design and development of new biofunctional nanomaterials based on sugar-peptide conjugates. Molecular self-assembly approach will be followed for bottom-up nanofabrication of these soft namomaterials to generate a variety of nanostructures. These supramolecular nanomaterial scaffolds will be explored towards solving the problems of biology (e.g. drug delivery, cancer therapy, regenerative medicine) and energy resources.
♦ Y. M. Abul-Haija, S. Roy, P. W. J. M. Frederix, N. Javid, V. Jayawarna and R.V. Ulijn, Biocatalytically Triggered Co-Assembly of Two-Component Core/Shell Nanofibers, Small 2014, 10, 973-979.
♦ S. Debnath, S. Roy and R.V. Ulijn, Peptide Nanofibers with Dynamic Instability through Non-Equilibrium Biocatalytic Assembly, J. Am. Chem. Soc. 2013, 135, 16789-16792.
♦ N. Javid, S. Roy, M. Zelzer, Z. Yang, J. Sefcik and R.V. Ulijn, Cooperative Self-Assembly of Peptide Gelators and Proteins, Biomacromolecules 2013, 14, 4368–4376.
♦ G. Scott, S. Roy, Y. M. Abul-Haija, S. Fleming, S. Bai and R.V. Ulijn, Pickering Stabilized Peptide Gel Particles as Tunable Microenvironments for Biocatalysis, Langmuir 2013, 29, 14321-14327.
♦ S. Roy, N. Javid, J. Sefcik, P. J. Halling, and R. V. Ulijn, Salt-Induced Control of Supramolecular Order in BiocatalyticHydrogelation, Langmuir 2012, 28, 16664–16670. (As Corresponding author).
♦ S. Roy, N. Javid, P. W. J. M. Frederix, D. A. Lamprou, A. J. Urquhart, N. T. Hunt, P. J. Halling, and R. V. Ulijn, Dramatic Specific Ion Effect in Supramolecular Hydrogels, Chem. Eur. J. 2012, 18, 11723-11731 (As Corresponding author).
♦ L. S. Birchall, S. Roy, V. Jayawarna, M. Hughes, E. Irvine, G. T. Okorogheye, N. Saudi, E. De Santis, T. Tuttle, A. A. Edwards and R. V. Ulijn, Exploiting CH-π Interactions in Supramolecular Hydrogels of Aromatic Carbohydrate Amphiphiles, Chem. Sci. 2011, 2, 1349-1355 (Selected as cover picture of the issue).
♦ N. Javid, K. Vogtt, S. Roy, A. R. Hirst, A. Hoell, I. W. Hamley, R. V. Ulijn and J. Sefcik, Supramolecular Structures of Enzyme Clusters, J. Phys. Chem. Lett. 2011, 2, 1395-1399.
♦ A. R. Hirst†, S. Roy†, M. Arora, A. K. Das, N. Hodson, P. Murray, N. Javid, J. Sefcik, J. Boekhoven, J.H. van Esch, S. Santabarbara, N. T. Hunt and R. V. Ulijn, Biocatalytic Induction of Supramolecular Order, Nature Chemistry, 2010, 2, 1089-1094 (†Authors contributed equally).
♦ D. Das, S. Roy, S. Debnath, and P. K. Das, Surfactant-Stabilized Small Hydrogel Particles in Oil: Hosts for Remarkable Activation of Enzymes in Organic Solvents. Chem. Eur. J. 2010, 16, 4911-4922.
♦ S. Roy, and P. K. Das, Antibacterial Hydrogels of Amino Acid-Based Cationic Amphiphiles. Biotech. Bioeng. 2008, 100, 756-764.
♦ S. Roy, A. Dasgupta, and P. K. Das. Alkyl Chain Length Dependent Hydrogelation of L-Tryptophan Based Amphiphile. Langmuir 2007, 23, 11769-11776.
♦ R. N. Mitra, D. Das, S. Roy, and P. K. Das, Structure and Properties of Low Molecular Weight Amphiphilic Peptide Hydrogelators. J. Phys. Chem. B 2007, 111, 14107-14113.
♦ A. Shome, S. Roy, and P. K. Das. Nonionic Surfactants: A Key to Enhance the Enzyme Activity at Cationic Reverse Micellar Interface. Langmuir 2007, 23, 4130-4136.
♦ S. Roy, A. Dasgupta, and P. K. Das, Tailoring of Horseradish Peroxidase Activity in Cationic Water-in-Oil Microemulsions. Langmuir 2006, 22, 4567-4573.
♦ K. Mohanta, A. J. Pal, S. Roy, and P. K. Das, A Control Over Accessibility of Immobilized Enzymes through Porous Coating Layer. J. Colloid Interface Sci. 2006, 304, 329-334.
♦ D. Das, A. Dasgupta, S. Roy, R. N. Mitra, S. Debnath, and P. K. Das, Water Gelation of an Amino Acid Based Hydrogelator. Chem. Eur. J. 2006, 12, 5068-5074 (Selected as cover picture of the issue).
♦ A. Dasgupta, R. N. Mitra, S. Roy, and P. K. Das, Asymmetric Resolution in Ester Reduction by NaBH4 at the Interface of Aqueous Aggregates of Amino Acid, Peptide, and Chiral Counter-ion based Cationic Surfactants. Chem. Asian. J. 2006, 1, 780-788.
♦ D. Mitra, I. Chakraborty, S. C. Bhattacharya, S. P. Moulik, S. Roy, D. Das, and P. K. Das, Physicochemical Studies on Cetylammonium Bromide and its Modified (mono-, di- and trihydroxyethylated) Head Group Analogues. Their Micellization Characteristics in Wwater and Thermodynamic and Structural Aspects of Water-in-Oil Microemulsion Formed with Them along with n-Hexanol and Isooctane. J. Phys. Chem. B 2006, 110, 11314-11326.
♦ S. Roy, D. Das, A. Dasgupta, R. N. Mitra, and P. K. Das, Amino Acid Based Cationic Surfactants in Aqueous Solutions: Physicochemical Study and Application of Supramolecular Chirality in Ketone Reduction. Langmuir 2005, 21, 10398-10404.
♦ D. Das, S. Roy, R. N. Mitra, A. Dasgupta and P. K. Das, Head Group Size or Hydrophilicity of Surfactant: the Major Regulator of Lipase Activity in Cationic w/o Microemulsions. Chem. Eur. J. 2005, 11, 4881-4889 (Selected as cover picture of the issue and frontispiece).
♦ R. N. Mitra, A. Dasgupta, D. Das, S. Roy, S. Debnath, and P. K. Das, Geometric Constraints at the Surfactant Head Group: Effect on Lipase Activity in Cationic Reverse Micelles. Langmuir 2005, 21, 12115-12123.
♦ D. Das, S. Roy, and P. K. Das, Efficient and Simple NaBH4 Reduction of Esters at Cationic Micellar Surface. Org. Lett. 2004, 6, 4133-4136.
♦ A. A. Edwards, L. S. Birchall, V. Jayawarna, S. Roy, M. Hughes, T. Tuttle, N. Saudi, G. Okorgheye, R. V. Ulijn, Fmoc Hydrogels from Aromatic Carbohydrate Amphiphiles, J. Pharm. Pharmacol.2010, 62, 1331-1332 (The UK-PharmSci Conference, The Science of Medicine, 1st –3rd September, 2010).
♦ N. Kayal, S. Roy, R. N. Mitra, P. K. Das, Antimicrobial Activity of Amino Acids and Dipeptide-based Amphiphiles, J. Biotech. 2008, 136, S28–S29 (Biotechnology for the Sustainability of Human Society, 13th International Biotechnology Symposium and Exhibition IBS 2008, 12th-17th October, China).
S. Roy and R.V. Ulijn, Exploiting Biocatalysis in the Synthesis of Supramolecular Polymers, Enzymatic Polymerisations, Advances in Polymer Science, 2010, 237, 127-143.
♦ S. Roy, 8th Chandigarh Science Congress (Chascon-2014), Panjab University, 26th-28th February, 2014.
♦ S. Roy, International Conference on Interdisciplinary areas with Chemical Sciences (ICIACS 2013), Panjab University, 30th October -1st November, 2013.
♦ S. Roy, R. V. Ulijn, Highly Tunable Gels via Non-equilibrium Biocatalytic Self-assembly, UK-India Symposium on Molecular Materials Chemistry, University of Strathclyde, UK, 13th September, 2012.
♦ S. Roy, R. V. Ulijn, Peptide Hydrogels via Non-equilibrium Biocatalytic Self-assembly, RAMS Meeting, University of Strathclyde, UK, 5th – 7th September, 2012.
♦ S. Roy, V. Jayawarna, R. V. Ulijn, Self-assembled Peptide Nanostructures: A Microscopic Insight, AFM Users Meeting, University of Strathclyde, UK, 22nd June, 2012.
♦ S. Roy, R. V. Ulijn, Biocatalytic Self-Assembly of Supramolecular Polymers, 10th International Conference in Materials Chemistry (MC10), University of Manchester, UK, 4th – 7th July, 2011.
♦ S. Roy, R. V. Ulijn, Non-equilibrium Biocatalytic Self-assembly, UK-India Symposium on Molecular Materials Chemistry, The Chemistry Centre, London, UK, 10th – 11th September, 2012.
♦ S. Roy, R. V. Ulijn, Highly tunable gels via biocatalytic non-equilibrium self-assembly, Bionanotechnology III: from biomolecular assembly to applications, Robinson College, Cambridge, UK, 4th – 6th January, 2012.
♦ S. Roy, V. Jayawarna, R. V. Ulijn, Design and Synthesis of Enzyme-Responsive Hydrogelators for Biomedical Application, Polymeric Biomaterials Conference, University of Reading, UK, 15th -16th April, 2010.
♦ S. Roy, V. Jayawarna, R. V. Ulijn, Design and Synthesis of Small Molecule Hydrogelators for Directing Cell Behaviour, Polymeric and self-assembling hydrogels. Macrogroup UK, University of Manchester, UK, 22nd – 23rd September, 2009.
♦ S. Roy, P. K. Das, L-Tryptophan based amphiphilic hydrogelators:potent for biomedicinal application, 10th CRSI-RSC (2nd) National Symposium in Chemistry, Indian Institute of Science, Bangalore, India, 31st January-3rd February, 2008- Poster.
♦ S. Roy, P. K. Das, Amino Acid Based Amphiphilic Hydrogelators: Potent for Antibacterial Activity and Controlled Release, Indo-German bilateral Seminar, Antimicrobial Drug Resistance and the Development of New Antibiotics, Indian National Science Academy, 22nd -25th November, 2007.
♦ D Das, S. Roy, A. Dasgupta, P. K. Das, Efficient and Stereoselective Ester Reduction by NaBH4 in Aqueous Self-Aggregates of Cationic Surfactants, National Symposium on Organic Chemistry-III, Department of Chemistry, Jadavpur University, Kolkata, 22nd- 23rd February, 2006.
♦ D Das, S. Roy, A. Dasgupta, P. K. Das, Efficient Ester Reduction Simply by NaBH4 in Aqueous Self-Aggregate of Cationic Surfactants, 8th CRSI National Symposium in Chemistry, Institute of Technology, Mumbai, India, 3rd – 5th February, 2006.
♦ S. Roy, D. Das, A. Dasgupta, R. N. Mitra, P. K. Das, Supramolecular Chirality in Aqueous Solution of Amino Acid Based Cationic Surfactants: Application to Ketone Reduction, Joint International Conference on Building Bridges, Forging Bonds for 21st Century Organic Chemistry and Chemical Biology (ACS-CSIR OCCB), National Chemical Laboratory, Pune, 6th -9th January, 2006.
♦ D. Das, S. Roy, R. N. Mitra, A. Dasgupta, P. K. Das, Predominant Role of Headgroup Size over Hydrophilicity in Micellar Enzymology, 3rdCRSI Symposium, Kolkata Chapter, Department of Chemistry, Indian Institute of Technology, Kharagpur, 6th August, 2005.
♦ A. Dasgupta, D. Das, R. N. Mitra, S. Roy, P. K. Das, Role of Microstructural Parameters in Micellar Enzymology, International Conference on Soft Matter, Park Hotel, Kolkata, 18th -20th November, 2004 –Poster.
CONTACT INFORMATION :
Tel: 0172 - 2210075
Email Id : sangita(at)inst(dot)ac(dot)in
Office Address :
Institute of Nano Science & Technology
Habitat Centre, Sector - 64, Phase X, Mohali