Faculty Directory

Dr. Deepa Ghosh

Professor (Scientist-F )

Research Interests

Tissue Engineering

Regenerative Medicine

Cancer Theranostics

Osteoarthritis

deepa.ghosh@inst.ac.in

  • Google Scholar Link
  • Research Interest

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    Research Highlights


    PhD Students

    • Mr. Munish Shorie

      Email: munish.ph14213@inst.ac.in

      Reg. No.: PH14213

      Working Since Aug, 2014
    • Ms. ANJANA SHARMA

      Email: anjana.ph16226@inst.ac.in

      Reg. No.: PH16226

      Working Since Jan, 2017
    • Mr. Himadri Shekhar Roy

      Email: himadri.ph18220@inst.ac.in

      Reg. No.: PH18220

      Working Since Aug, 2018
    • Mr. JIJO THOMAS

      Email: jijo.ph16231@inst.ac.in

      Reg. No.: PH16231

      Working Since Jan, 2017
    • Ms.Vianni Chopra

      Email: vianni.ph17201@inst.ac.in

      Reg. No.: PH17201

      Working Since Aug, 2017

    Post Doc Fellows

    • Dr Swati Kaushik

      Email: swatitabi@gmail.com

      Reg. No.: Rp.74/RGCB

      Working Since Jan, 2018
    • Dr. Vineeta Panwar

      Email: vineeta.pdf1713@inst.ac.in

      Reg. No.: RP-622042

      Working Since Jan, 2018

    Project - JRF/SRF

    • Rupali Singh

      Email: rupalis0104@gmail.com

      Reg. No.: RP691921


    1. A bioinspired, ice-templated multifunctional 3D cryogel composite crosslinked through in situ reduction of GO displayed improved mechanical, osteogenic and antimicrobial properties: Vianni Chopra, Jijo Thomas, Anjana Sharma, Vineeta Panwar, Swati Kaushik, Deepa Ghosh, (2021) Materials Science & Engineering C, 119: 111584. DOI: 10.1016/j.msec.2020.111584

    2. Synthesis and Evaluation of a Zinc Eluting rGO/Hydroxyapatite Nanocomposite Optimized for Bone Augmentation: Vianni Chopra, Jijo Thomas, Anjana Sharma, Vineeta Panwar, Swati Kaushik, Shivani Sharma, Konica Porwal, Chirag Kulkarni, Swati Rajput, Himalaya Singh, Kumaravelu Jagavelu, Naibedya Chattopadhyay, and Deepa Ghosh, (2020) ACS Biomater. Sci. Eng., . DOI: 10.1021/acsbiomaterials.0c00370

    3. Synthesis and Evaluation of a Zinc Eluting rGO/Hydroxyapatite Nanocomposite Optimized for Bone Augmentation: . V. Chopra, J. Thomas, A. Sharma, V. Panwar, S. Kaushik, S. Sharma, K. Porwal, C. Kulkarni, S. Rajput, H. Singh, K. Jagavelu, N. Chattopadhyay and D. Ghosh*, (2020) ACS Biomater. Sci. Eng., 6, 12: 6710–6725. DOI: 10.1021/acsbiomaterials.0c00370

    4. Molecular docking and molecular dynamics to identify collagenase inhibitors as lead compounds to address osteoarthritis: Himadri Shekhar Roy,Gurudutt Dubey,VishnuKumar Sharma,Prasad V Bharatam,Deepa Ghosh, (2020) Journal of Biomolecular Structure and Dynamics, . DOI: 10.1080/07391102.2020.1838326

    5. Nanotechnology for COVID-19: Therapeutics and Vaccine Research: G. Chauhan, M J. Madou, S. Kalra, V. Chopra, D. Ghosh, and Sergio O Martinez-Chapa, (2020) ACS Nano, 14, 7: 7760–7782. DOI: 10.1021/acsnano.0c04006

    6. Water-Templated, Polysaccharide-rich Bioartificial 3D Microarchitectures as Extra-Cellular Matrix Bioautomatons: Swati Kaushik, Sonu Gandhi, Mehak Chauhan, Shaohua Ma, Souvik Das, Deepa Ghosh, Aneesh Chandrasekharan, Md Bayazeed Alam, Avanish Singh Parmar, Alpana Sharma, T. R. Santhoshkumar and Deepa Suhag, (2020) ACS Applied Materials & Interfaces, . DOI: 10.1021/acsami.0c01012

    7. In-vitro and in-vivo evaluation of modified sodium starch glycolate for exploring its haemostatic potential: Vineeta Panwara, Jijo Thomasa, Anjana Sharmaa, Vianni Chopraa, Swati Kaushika, Ashutosh Kumarb and Deepa Ghosha*, (2020) Carbohydrate Polymers, 235: 115975. DOI: 10.1016/j.carbpol.2020.115975

    8. In Situ Biosynthesized Superparamagnetic Iron Oxide Nanoparticles (SPIONS) Induce Efficient Hyperthermia in Cancer Cells: Swati Kaushik,Jijo Thomas,Vineeta Panwar,Hasan Ali,Vianni Chopra,Anjana Sharma,Ruchi Tomar, Deepa Ghosh, (2020) ACS Appl. Bio Mater, 3: 779-788. DOI: 10.1021/acsabm.9b00720

    9. In-vitro and In-vivo evaluation of biocompatible and biodegradable calcium-modified carboxymethyl starch as a topical hemostat: Vineeta Panwara, Anjana Sharmaa, Jijo Thomasa, Vianni Chopraa, Swati Kaushika, Ashutosh Kumar,Deepa Ghosh, (2019) Materalia, 2: 103373. DOI: https://doi.org/10.1016/j.mtla.2019.100373

    10. Interaction of Carbon Dots with Endothelial Cells: Implications for Biomedical Applications: Anjana Sharma, Vineeta Panwar, Vianni Chopra, Jijo Thomas, Swati Kaushik,Deepa Ghosh, (2019) ACS Applied Nano Materials, 1: 08. DOI: 10.1021/acsanm.9b01080

    11. Polysaccharide-Based Hybrid Self-Healing Hydrogel Supports the Paracrine Response of Mesenchymal Stem Cells.: Jijo Thomas, Anjana Sharma, Vineeta Panwar, Vianni Chopra, and Deepa Ghosh*, (2019) ACS Applied Biomaterials, . DOI: 10.1021/acsabm.9b00074

    12. Paracrine factors secreted by umbilical cord-derived MSCs induce angiogenesis in vitro by a VEGF-independent pathway.: P. Kuchroo, V. Dave, A. Kumar, C. Viswanathan,Deepa Ghosh, (2015) Stem Cells and Development, 24(4): 437-450. DOI: 10.1089/scd.2014.0184

    13. Preparation and characterization of silver nanoparticle loaded amorphous hydrogel of carboxymethylcellulose for infected wounds.: A. Das, A.Kumar, N.Patil, C. Viswanathan,Deepa Ghosh, (2015) Carbohydrate Polymers, 130: 254–261. DOI: 10.1016/j.carbpol.2015.03.082

    14. A Non-invasive Method to Evaluate the Efficacy of Human Myoblast in Botulinum-A Toxin Induced Stress Urinary Incontinence Model in Rats.: B. Bandyopadhyay, A. Thakur, V. Dave, C.Viswanathan,Deepa Ghosh, (2014) Urology Journal, 10: 1126-1134.

    15. Role of cell therapy in non-healing diabetic ulcers in patients with severe peripheral arterial disease – a preliminary report on five cases.: C. Viswanathan, P. Shetty, S. Sarang, K .Cooper, A. Bal,Deepa Ghosh, (2013) The Journal of Diabetic Foot Complications, 5: 1-14.

    16. Evaluation of L-lactide/ε-caprolactone copolymer Scaffold to support Myoblast Growth and Differentiation.: B. Bandyopadhyay, V. Shah, M. Soram, C. Viswanathan,Deepa Ghosh, (2013) Biotechnology Progress, 29: 197-205. DOI: 10.1002/btpr.1665

    17. Efficacy and Safety of Autologous Cultured Melanocytes Delivered on Poly (DL-Lactic Acid) Film: A Prospective, Open-Label, Randomized, Multicenter Study: P.Kuchroo, C.Viswanathan, S.Sachan, B.Shah, D.Bhatt, S.G.Parasramani, S.Savant,D.Ghosh, (2012) Dermatol Surg, 10: 1–10. DOI: 10.1111/dsu.12000

    18. Immunologic properties of human dermal fibroblasts.: M. Deshpande, S. Tipnis, P. Shetty,C. Viswanathan,Deepa Ghosh, (2010) Human Immunology, 71: 1089-1098. DOI: 10.1016/j.humimm.2010.08.003

    19. Cultured Melanocytes: From skin biopsy to transplantation.: S. Shenoy ,P. Kuchroo.,Deepa Ghosh, (2008) Cell Transplantation, 17(3): 351-60. DOI: 10.3727/096368908784153869

    20. Hepatocyte Growth Factor induces myoblast proliferation but inhibits its differentiation: K.Miller, S. Matteson ,GK. Pavlath,Deepa Thaloor, (1999) Am J Physiol Cell Physiol. Jan, 278 (1): C174-81.

    21. Systemic administration of the NF-kappa B inhibitor curcumin stimulates muscle regeneration after traumatic injury.: J. Gephardt, K. Miller, GK. Pavlath,Deepa Thaloor, (1999) Am.J. Physiol., 277(2 Pt 1): C320-C329. DOI: 10.1152/ajpcell.1999.277.2.C320

    22. Activation and Cellular localization of the Cyclosporine A- sensitive transcription factor NF-AT in skeletal muscle cells: KL. Abbott, B. Friday, TJ. Murphy and GK. Pavlath.,Deepa Thaloor, (1998) Mol. Bio. Cell, 9(10): 2905-16. DOI: 10.1091/mbc.9.10.2905

    23. Heterogeneity among muscle precursor cells in adult skeletal muscles with differing regenerative capacities: GK. Pavlath, TA. Rando, M. Cheong,AW. English,B.Zheng.,Deepa Thaloor, (1998) Developmental Dynamics, 212: 495-508. DOI: 10.1002/(SICI)1097-0177(199808)212:4<495::AID-AJA3>3.0.CO;2-C

    24. Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by Curcumin: AK. Singh, GS. Sidhu, PV. Prasad,H.Kleinman,RK. Maheshwari,Deepa Thaloor, (1998) Cell Growth and Differentiation, 9(4): 305-312. DOI: 10.1016/0304-3835(96)04357-1

    25. Enhancement of Wound Healing by Curcumin in animals. Wound Repair and Regeneration: GS. Sidhu, AK. Singh, KK. Banaudha, G. Patnaik, RC. Srimal and RK. Maheshwari.,Deepa Thaloor, (1998) 6(2): 167-77. DOI: 10.1046/j.1524-475X.1998.60211.x

    26. Enhanced biosynthesis of extracellular matrix proteins and TGF-b by Polyinosinic-Polycytidylic acid during cutaneous wound healing in vivo: GS. Sidhu, AK. Singh, PN. Raghunath and RK. Maheshwari.,Deepa Thaloor, (1996) J. Cell. Physiol., 169(1): 108-114 (Cited 10) IF 4.218. DOI: 10.1002/(SICI)1097-4652(199610)169

    27. Curcumin inhibits the proliferation and cell cycle progression of human umbilical vein endothelial cell: AK. Singh, GS. Sidhu,RK. Maheshwari.,Deepa Thaloor, (1996) Cancer Lett., 107: 109-115. DOI: 10.1016/0304-3835(96)04357-1

    1. Device for culturing and transporting cells.: Sudheer Shenoy,Deepa Ghosh, (2016) (US Patent 7,713,734; EP Patent 1,979,465)., .

    2. Insert Device for culturing cells.: Pushpa Choudhary,Deepa Ghosh, (2015) (US patent 7,588,932; Indian patent 236218), .

    3. Cultured Melanocytes on Bioploymer Membranes for Treatment of Hyper and Hypopigmentation Disorders.: Sudheer Shenoy, Pushpa Kuchroo,Viru Shah,Deepa Ghosh, (2014) (Patent: US 20080089870A1, EP2089076; PCT/IN2007/000489), .

    4. An interactive wound cover.: Pushpa Kuchroo, Sudheer Shenoy, Vidhya Rangaswamy, Sonti Venkata Rama Krishna,Deepa Ghosh, (2013) (US 20070258958A1; PCT/IN2007/000060), .

    5. Hydrogel composition.: Joydeep Dutta, Anish Sen Majumdar, Garima Dwivedi, Chandra Viswanathan,Deepa Ghosh, (2012) (Patent: PCT/IN2009/000707, WO2010067378A2), .

    6. A process for preparing keratinocyte composition as a wound cover.: Pushpa Kuchroo, Sudheer Shenoy, Vidhya Rangaswamy, Sonti Venkata Rama Krishna,Deepa Ghosh, (2011) ( Indian patent No: 243296), .

    1. “Stem Cells and Tissue Engineering: From Bench to bedside” at the International conference on Biomaterials, Artificial organs and Tissue Engineering,: Deepa Ghosh, (2010) .

    2. “Systemic administration of Curcumin an NFkB/AP-1 inhibitor enhances muscle regeneration in mice” at the Gordon conference, Tilton, NH,: Deepa Thaloor, (1998) .

    3. “The effect of HGF on regeneration in mice in the Satellite Meeting”, Boston, MA,: USA, (1998) .

    4. Inhibition of angiogenesis of Human Umbilical Vein endothelial cells by Curcumin” at the American Society of Cell Biology in Washington DC: Deepa Thaloor, (1995) .

    5. Thymosin-b4 enhances angiogenesis in endothelial cell” in the XVI International Cancer Congress, New Delhi,: Deepa Thaloor, (1994) .

    6. Anti-proliferative effect of Curcumin” in the American Society of Cell Biology at San Francisco, CA: Deepa Thaloor, (1994) .

    7. Brefeldin-A inhibits HTLVIII replication in peripheral blood lymphocytes” in the First National Conference on Human Retroviruses and Related Infections, Washington DC.: Deepa Thaloor, (1993) .

    8. Interferon induced block in the transport of VSV-G in TGN in transfected mouse cells” in The American Society of Cell Biology at New Orleans, LO,: Deepa Thaloor, (1993) .

    Fundings

    • Teachers Associateship for Research Excellence (TARE) 3 years, DST-SERB
      Funding Amount: 1830OOO
      PI: Dr. Deepa Ghosh
    • Drug-hydrogel prototypes for in situ containment of oral cancer 2 years, RGCB, Trivandrum
      Funding Amount: 2000000
      PI: Dr. Deepa Ghosh
    • Addressing Diabetic Foot Ulcers by using a Tissue Engineering Approach 3 years, DST-SERB
      Funding Amount: 5576440
      PI: Dr. Deepa Ghosh
    • Development of advanced third generation matrix associated chondrocytes for cartilage repair 3 years, Department of Biotechnology
      Funding Amount: 12298400
      PI: Dr. Deepa Ghosh

    • 1995

      PhD

      Birla Institute of Technology and Science (BITS), Pilani, India; Uniformed Services University of the Health Sciences Bethesda, MD. USA

    • 1991

      M. Pharm

      Birla Institute of Technology and Science (BITS), Pilani, India

    • 1989

      B.Pharm

      Madras University

    • Professor (Scientist-F):Institute of Nano Science and Technology,, Mohali, India (September 2016 to Present till date )

    • Freelance Consultant:Freelance Consultant, Maharashtra, India (March 2014 to April 2016 )

    • Associate Research Director:Reliance Life Sciences, Navi- Mumbai,, Maharashtra, India (April 2009 to March 2014 )

    • Assistant Research Director:Tissue Engineering and Wound Management, Reliance Life Sciences, Navi- Mumbai,, Maharashtra, India (April 2005 to April 2009 )

    • Senior Research Scientist:Tissue Engineering, Reliance Life Sciences,, Mumbai, India (March 2001 to April 2004 )

    • Research Scientist I:Pharmacology Department, Glenmark Pharma,, Mumbai, India (March 2000 to May 2001 )

    • Research Leader:Natural products, Quest Institute, Nicholas Piramal,, Mumbai, India (March 1999 to April 2000 )

    • Postdoctoral research fellow:Emory University, Atlanta,, GA, USA (February 1996 to April 1999 )

    • Research Fellow:Henry M. Jackson Foundation, USUHS,, MD, USA (March 1992 to October 1996 )

    • Lecturer:Department of Pharmacy, Birla Institute of Technology and Sciences,, Pilani, India (March 1991 to November 1992 )

    Awards & Honours

    • Recipient of the NASI-Reliance Innovation award (2012)
    • Best research award from Henry M. Jackson Foundation for the Advancement of Military Medicine (1994)

    Professional Recognitions