Faculty Directory

Dr. Deepa Ghosh

Professor (Scientist-F )

Tissue engineering using nanostructured scaffolds. Cell delivery using nanocomposites. Addressing wound management with low cost devices.

CONTACT INFORMATION :

Research Interest



  • Tissue engineering using nanostructured scaffolds. Cell delivery using nanocomposites. Addressing wound management with low cost devices.

Research Highlights

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Project - JRF/SRF

  • Rupali Singh

    Email: rupali.rp691921@inst.ac.in

    Reg. No.: RP691921

    Working Since Oct, 2019

PhD Students

  • Mr. Himadri Shekhar Roy

    Email: himadri.ph18220@inst.ac.in

    Reg. No.: PH18220

    Working Since Aug, 2018
  • Ms.Vianni Chopra

    Email: vianni.ph17201@inst.ac.in

    Reg. No.: PH17201

    Working Since Aug, 2017
  • Mr. JIJO THOMAS

    Email: jijo.ph16231@inst.ac.in

    Reg. No.: PH16231

    Working Since Jan, 2017
  • Ms. ANJANA SHARMA

    Email: anjana.ph16226@inst.ac.in

    Reg. No.: PH16226

    Working Since Dec, 2016
  • Mr. Munish Shorie

    Email: munish.ph14213@inst.ac.in

    Reg. No.: PH14213

    Working Since Jul, 2014

Post Doc Fellows

  • Dr. Vineeta Panwar

    Email: vineeta.pdf1713@inst.ac.in

    Reg. No.: RP-622042

    Working Since Feb, 2018
  • Dr Swati Kaushik

    Email: swatitabi@gmail.com

    Reg. No.: Rp.74/RGCB

    Working Since Mar, 2018

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  1. In-vitro and in-vivo evaluation of modified sodium starch glycolate for exploring its haemostatic potential: V. Panwar,J. Thomas, A Sharma,V Chopra,S Kaushik,A Kumar , D Ghosh, (2020) Carbohydrate Polymers, 235: 115975. DOI: 10.1016/j.carbpol.2020.115975

  2. In Situ Biosynthesized Superparamagnetic Iron Oxide Nanoparticles (SPIONS) Induce Efficient Hyperthermia in Cancer Cells: Swati Kaushik,Jijo Thomas,Vineeta Panwar,Hasan Ali,Vianni Chopra,Anjana Sharma,Ruchi Tomar, Deepa Ghosh, (2020) ACS Appl. Bio Mater, 3: 779-788. DOI: 10.1021/acsabm.9b00720

  3. In-vitro and In-vivo evaluation of biocompatible and biodegradable calcium-modified carboxymethyl starch as a topical hemostat: Vineeta Panwara, Anjana Sharmaa, Jijo Thomasa, Vianni Chopraa, Swati Kaushika, Ashutosh Kumar, (2019) Materalia, 2: 103373. DOI: https://doi.org/10.1016/j.mtla.2019.100373

  4. Interaction of Carbon Dots with Endothelial Cells: Implications for Biomedical Applications: Anjana Sharma, Vineeta Panwar, Vianni Chopra, Jijo Thomas, Swati Kaushik, (2019) ACS Applied Nano Materials, 1: 08. DOI: 10.1021/acsanm.9b01080

  5. Polysaccharide-Based Hybrid Self-Healing Hydrogel Supports the Paracrine Response of Mesenchymal Stem Cells.: J. Thomas, A. Sharma, V. Panwar, V. Chopra, (2019) ACS Applied Biomaterials, . DOI: 10.1021/acsabm.9b00074

  6. Paracrine factors secreted by umbilical cord-derived MSCs induce angiogenesis in vitro by a VEGF-independent pathway.: P. Kuchroo, V. Dave, A. Kumar, C. Viswanathan, (2015) Stem Cells and Development, 24(4): 437-450. DOI: 10.1089/scd.2014.0184

  7. Preparation and characterization of silver nanoparticle loaded amorphous hydrogel of carboxymethylcellulose for infected wounds.: A. Das, A.Kumar, N.Patil, C. Viswanathan, (2015) Carbohydrate Polymers, 130: 254–261. DOI: 10.1016/j.carbpol.2015.03.082

  8. A Non-invasive Method to Evaluate the Efficacy of Human Myoblast in Botulinum-A Toxin Induced Stress Urinary Incontinence Model in Rats.: B. Bandyopadhyay, A. Thakur, V. Dave, C.Viswanathan, (2014) Urology Journal, 10: 1126-1134.

  9. Role of cell therapy in non-healing diabetic ulcers in patients with severe peripheral arterial disease – a preliminary report on five cases.: C. Viswanathan, P. Shetty, S. Sarang, K .Cooper, A. Bal, (2013) The Journal of Diabetic Foot Complications, 5: 1-14.

  10. Evaluation of L-lactide/ε-caprolactone copolymer Scaffold to support Myoblast Growth and Differentiation.: B. Bandyopadhyay, V. Shah, M. Soram, C. Viswanathan, (2013) Biotechnology Progress, 29: 197-205. DOI: 10.1002/btpr.1665

  11. “Measures to overcome the challenges facing cell delivery in regenerative medicine” in the Stem Cells 2012 conference in: Mumbai, (2012) .

  12. Efficacy and Safety of Autologous Cultured Melanocytes Delivered on Poly (DL-Lactic Acid) Film: A Prospective, Open-Label, Randomized, Multicenter Study: P.Kuchroo, C.Viswanathan, S.Sachan, B.Shah, D.Bhatt, S.G.Parasramani, S.Savant, (2012) Dermatol Surg, 10: 1–10. DOI: 10.1111/dsu.12000

  13. Immunologic properties of human dermal fibroblasts.: M. Deshpande, S. Tipnis, P. Shetty,C. Viswanathan, (2010) Human Immunology, 71: 1089-1098. DOI: 10.1016/j.humimm.2010.08.003

  14. Cultured Melanocytes: From skin biopsy to transplantation.: S. Shenoy ,P. Kuchroo., (2008) Cell Transplantation, 17(3): 351-60. DOI: 10.3727/096368908784153869

  15. Systemic administration of the NF-kappa B inhibitor curcumin stimulates muscle regeneration after traumatic injury.: J. Gephardt, K. Miller, GK. Pavlath, (1999) Am.J. Physiol., 277(2 Pt 1): C320-C329. DOI: 10.1152/ajpcell.1999.277.2.C320

  16. Hepatocyte Growth Factor induces myoblast proliferation but inhibits its differentiation: K.Miller, S. Matteson ,GK. Pavlath, (1999) Am J Physiol Cell Physiol. Jan, 278 (1): C174-81.

  17. Enhancement of Wound Healing by Curcumin in animals. Wound Repair and Regeneration: GS. Sidhu, AK. Singh, KK. Banaudha, G. Patnaik, RC. Srimal and RK. Maheshwari., (1998) 6(2): 167-77. DOI: 10.1046/j.1524-475X.1998.60211.x

  18. Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by Curcumin: AK. Singh, GS. Sidhu, PV. Prasad,H.Kleinman,RK. Maheshwari, (1998) Cell Growth and Differentiation, 9(4): 305-312. DOI: 10.1016/0304-3835(96)04357-1

  19. Heterogeneity among muscle precursor cells in adult skeletal muscles with differing regenerative capacities: GK. Pavlath, TA. Rando, M. Cheong,AW. English,B.Zheng., (1998) Developmental Dynamics, 212: 495-508. DOI: 10.1002/(SICI)1097-0177(199808)212:4<495::AID-AJA3>3.0.CO;2-C

  20. Activation and Cellular localization of the Cyclosporine A- sensitive transcription factor NF-AT in skeletal muscle cells: KL. Abbott, B. Friday, TJ. Murphy and GK. Pavlath., (1998) Mol. Bio. Cell, 9(10): 2905-16. DOI: 10.1091/mbc.9.10.2905

  21. Enhanced biosynthesis of extracellular matrix proteins and TGF-b by Polyinosinic-Polycytidylic acid during cutaneous wound healing in vivo: GS. Sidhu, AK. Singh, PN. Raghunath and RK. Maheshwari., (1996) J. Cell. Physiol., 169(1): 108-114 (Cited 10) IF 4.218. DOI: 10.1002/(SICI)1097-4652(199610)169

  22. Curcumin inhibits the proliferation and cell cycle progression of human umbilical vein endothelial cell: AK. Singh, GS. Sidhu,RK. Maheshwari., (1996) Cancer Lett., 107: 109-115. DOI: 10.1016/0304-3835(96)04357-1

  1. Device for culturing and transporting cells.: Sudheer Shenoy, (2016) (US Patent 7,713,734; EP Patent 1,979,465)., .

  2. Insert Device for culturing cells.: Pushpa Choudhary, (2015) (US patent 7,588,932; Indian patent 236218), .

  3. Cultured Melanocytes on Bioploymer Membranes for Treatment of Hyper and Hypopigmentation Disorders.: Sudheer Shenoy, Pushpa Kuchroo,Viru Shah, (2014) (Patent: US 20080089870A1, EP2089076; PCT/IN2007/000489), .

  4. An interactive wound cover.: Pushpa Kuchroo, Sudheer Shenoy, Vidhya Rangaswamy, Sonti Venkata Rama Krishna, (2013) (US 20070258958A1; PCT/IN2007/000060), .

  5. Hydrogel composition.: Joydeep Dutta, Anish Sen Majumdar, Garima Dwivedi, Chandra Viswanathan, (2012) (Patent: PCT/IN2009/000707, WO2010067378A2), .

  6. A process for preparing keratinocyte composition as a wound cover.: Pushpa Kuchroo, Sudheer Shenoy, Vidhya Rangaswamy, Sonti Venkata Rama Krishna, (2011) ( Indian patent No: 243296), .

  1. “Safety and effi cacy study of autologous cultured melanocytes delivered on Poly (lactic acid) membrane (ReliDerm®M) in thebtreatment of Stable Vitiligo”. International Conference & Exhibitio: USA, (2019) .

  2. “Regenerative medicine and Tissue Engineering” in the 82nd Annual Session of the National Academy of Sciences, India and National Symposium on “Nano-science & Technology for Mankind” on Nov 2: Varanasi, (2012) .

  3. “Tissue engineering approach to cell delivery” at International Conference on Emerging Cell Therapies, Chicago,: USA, (2012) .

  4. “Autologous Cultured Melanocytes delivered on Poly (lactic acid) membrane (ReliDerm®M) in the treatment of Stable Vitiligo: Safety and Efficacy study” at Vitilicon 2011 conference,: Bangalore, (2011) .

  5. “Challenges in addressing wounds in India”. Wound healing congress, Dallas, Texas,: USA, (2011) .

  6. “Stem Cells and Tissue Engineering: From Bench to bedside” at the International conference on Biomaterials, Artificial organs and Tissue Engineering,: Cochin, (2010) .

  7. “Chitosan: A potential keratinocyte delivery system for wound management” at the Gordon conference, Plymouth, NH,: USA, (2005) .

  8. “Systemic administration of Curcumin an NFkB/AP-1 inhibitor enhances muscle regeneration in mice” at the Gordon conference, Tilton, NH,: USA, (1998) .

  9. “The effect of HGF on regeneration in mice in the Satellite Meeting”, Boston, MA,: USA, (1998) .

  10. Inhibition of angiogenesis of Human Umbilical Vein endothelial cells by Curcumin” at the American Society of Cell Biology in Washington DC: USA, (1995) .

  11. Thymosin-b4 enhances angiogenesis in endothelial cell” in the XVI International Cancer Congress, New Delhi,: India, (1994) .

  12. Anti-proliferative effect of Curcumin” in the American Society of Cell Biology at San Francisco, CA: USA, (1994) .

  13. Brefeldin-A inhibits HTLVIII replication in peripheral blood lymphocytes” in the First National Conference on Human Retroviruses and Related Infections, Washington DC.: USA, (1993) .

  14. Interferon induced block in the transport of VSV-G in TGN in transfected mouse cells” in The American Society of Cell Biology at New Orleans, LO,: USA, (1993) .

Fundings

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  • 1995

    PhD

    Birla Institute of Technology and Science (BITS), Pilani, India; Uniformed Services University of the Health Sciences Bethesda, MD. USA

  • 1991

    M. Pharm

    Birla Institute of Technology and Science (BITS), Pilani, India

  • 1989

    B.Pharm

    Madras University

  • Professor (Scientist-F):Institute of Nano Science and Technology,, Mohali, India (September 2016 to Present till date )

  • Freelance Consultant:Freelance Consultant, Maharashtra, India (March 2014 to April 2016 )

  • Associate Research Director:Reliance Life Sciences, Navi- Mumbai,, Maharashtra, India (April 2009 to March 2014 )

  • Assistant Research Director:Tissue Engineering and Wound Management, Reliance Life Sciences, Navi- Mumbai,, Maharashtra, India (April 2005 to April 2009 )

  • Senior Research Scientist:Tissue Engineering, Reliance Life Sciences,, Mumbai, India (March 2001 to April 2004 )

  • Research Scientist I:Pharmacology Department, Glenmark Pharma,, Mumbai, India (March 2000 to May 2001 )

  • Research Leader:Natural products, Quest Institute, Nicholas Piramal,, Mumbai, India (March 1999 to April 2000 )

  • Postdoctoral research fellow:Emory University, Atlanta,, GA, USA (February 1996 to April 1999 )

  • Research Fellow:Henry M. Jackson Foundation, USUHS,, MD, USA (March 1992 to October 1996 )

  • Lecturer:Department of Pharmacy, Birla Institute of Technology and Sciences,, Pilani, India (March 1991 to November 1992 )

Awards & Honours

  • Recipient of the NASI-Reliance Innovation award (2012)
  • Best research award from Henry M. Jackson Foundation for the Advancement of Military Medicine (1994)

Professional Recognitions